Being ignorant of the Creator and His good attributes is detrimental to trust in GD.  For whoever fails to appreciate the Creator's compassion for His creatures, His protection of them, His providence, dominion, and control over them will not be confident in Him and will not rely on Him.  Another thing that is detrimental is ignorance of the Creator's command i.e.,  His Torah, in which he charged us to rely on Him and to trust in Him pg 465